Test Your Knowledge of Sjögren's Disease Recognition and Risk
Reviewed by: HU Medical Review Board | Last reviewed: August 2026 | Last updated: August 2026
Sjögren's disease is diagnosed late more often than it is diagnosed early, and the reasons are distributed across the workup – weighted classification criteria that are easy to misapply, imaging that is specific but insensitive, and risk stratification that rests on a small number of laboratory findings. Test what you know about cover recognition, diagnostic testing, and malignancy risk with these 5 questions.
Clinical Challenge
Under the 2016 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for primary Sjögren's disease, which combination of findings reaches the classification threshold?
Clinical Challenge
A prior diagnosis of which condition does not exclude a patient from classification under the 2016 ACR/EULAR criteria?
Clinical Challenge
In a patient being evaluated for Sjögren's disease, what does a normal salivary gland ultrasound establish?
Clinical Challenge
A patient with Sjögren's disease has persistent parotid enlargement. Which laboratory finding most strongly raises concern for mucosa-associated lymphoid tissue (MALT) lymphoma?
Clinical Challenge
A pulmonologist refers a patient with interstitial lung disease (ILD) of undetermined cause who reports no sicca symptoms. What do consensus guidelines on pulmonary disease in Sjögren's recommend?